CSIR NET Unit 4: Cell Communication & Cell Signalling


Unit 4 has a very good weightage in CSIR NET and its evitable from ths topics. Here we present important aspects of this unit:

Cell communication and cell signaling

  • Host parasite interaction Recognition and entry processes of different pathogens like bacteria, viruses into animal and plant host cells, alteration of host cell behavior by pathogens, virus-induced cell transformation, pathogen-induced diseases in animals and plants, cell-cell fusion in both normal and abnormal cells.
  • Cell signaling Hormones and their receptors, cell surface receptor, signaling through G-protein coupled receptors, signal transduction pathways, second
    messengers, regulation of signaling pathways, bacterial and plant twocomponent
    systems, light signaling in plants, bacterial chemotaxis and quorum
  • Cellular communication Regulation of hematopoiesis, general principles of cell
    communication, cell adhesion and roles of different adhesion molecules, gap
    junctions, extracellular matrix, integrins, neurotransmission and its regulation.
  • Cancer
    Genetic rearrangements in progenitor cells, oncogenes, tumor suppressor genes,
    cancer and the cell cycle, virus-induced cancer, metastasis, interaction of cancer
    cells with normal cells, apoptosis, therapeutic interventions of uncontrolled cell
  • Innate and adaptive immune system Cells and molecules involved in innate
    and adaptive immunity, antigens, antigenicity and immunogenicity. B and T cell
    epitopes, structure and function of antibody molecules. generation of antibody
    diversity, monoclonal antibodies, antibody engineering, antigen-antibody
    interactions, MHC molecules, antigen processing and presentation, activation
    and differentiation of B and T cells, B and T cell receptors, humoral and cellmediated
    immune responses, primary and secondary immune modulation, the
    complement system, Toll-like receptors, cell-mediated effector functions,
    inflammation, hypersensitivity and autoimmunity, immune response during
    bacterial (tuberculosis), parasitic (malaria) and viral (HIV) infections, congenital
    and acquired immunodeficiencies, vaccines.

Course Reviews


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  1. Nice course


    Impressive but not complete..